====== TISSUE FIXATION ======

  * Tissue fixation 
    * aim and objectives of fixation 
      * prevent autolysis and putrefaction of sample 
      * cause 
        * coagulation of tissue 
          * to prevent loss of diffusible substances 
          * stabilization of proteins
      * to fortify or increase strength of tissue specimen
      * to make favorable condition for stains  
    * tissue fixatives or chemical fixatives
      * Crosslinking fixatives – aldehydes
        * formaldehyde or formalin 
        * glutaraldehyde 
      * Precipitating (denaturing ) fixatives – alcohols
        * Ethyl Alcohol 
        * methanol ( sometimes)
      * oxidising agents
        * for histology 
          * potassium dichromate 
          * potassium permanganate 
          * chromic acid 
        * for electron microscopy 
          * osmium tetroxide
      * mercurials 
        * use 
          * increases staining brightness 
          * but slow permeability 
        * types 
          * mercuric chloride 
          * zenker's fixative
      * Picrates  
      * bouins fluid 
      * Karnovsky fixative 


===== TISSUE FIXATIVES =====



==== Formaldehyde or formalin ====


==== bouins fluid ====



==== Glutaraldehyde ====



==== Mercuric chloride ====



==== Potassium Dichromate ====



==== Ethyl Alcohol ====