Show pageOld revisionsBacklinksBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. ====== Thymus ====== {{:histology:thymus.png?500px}} * Composed of epithelial cells (endoderm, important for T lymphocyte differentiation), Hassall corpuscles (regressed epithelial cells), T cells of varying phenotypes; B cells in thymic medulla and thymic perivascular space (increase with age, Hum Pathol 2001;32:926); also interdigitating reticulum cells, Langerhans cells, mast cells, eosinophils, stromal cells * Dendritic cells modulate autoimmune regulation through tissue restricted antigens (TSA) and promote central tolerance in thymus (Am J Pathol 2010;176:1104) * Wnt4 regulates thymic cellularity through expansion of thymic epithelial cells and early thymic progenitors. en/thymus.txt Last modified: 2023/07/05 07:38by 127.0.0.1