====== GOLD STANDARDS IN PULMONOLOGY ====== * Gold standard method for diagnosis and treatment of Ventilator AssociatedPneumonia (VAP) - Broncho * alveolar lavage * Gold standard approach for resection of anterior and middle mediastinal masses -median or lateral * thoracotomy * Gold standard investigation for diagnosis of of lung infection (Radiotherapyinduced) in a cancer patient - * open-lung biopsy * Gold standard method for evaluation of respiratory gas exchange - ABG * Gold standard investigation for diagnosis of histoplasmosis - Fungal Culture * Gold standard investigation for diagnosis of HSV Encephalitis - Brain biopsy (CSFPCR largely replaced brain * biopsy in recent times) * Gold standard investigation for diagnosis of Tuberculous meningitis - Culture of CSF * Gold standard method for estimating resting energy expenditure - indirect calorimetry * Gold standard investigation for diagnosis of pertussis - Culture of nasopharyngeal secretions * Gold standard investigation for diagnosis of acute pharyngitis - Throat culture