Show pageOld revisionsBacklinksBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. ====== CHROMOSOMAL DISORDERS ====== * disorders in structure of chromosome * Due to break in chromosomes some part of chromosome containing important genes is lost * DELETION * types * microscopic deletions * deletion of short arm of chromosome 5 * cri-du chat syndrome * short arm of chromosome 4 * wolf-hirschhborn syndrome * submicroscopic microdeletions * syndrome * prader villi syndrome * angelmann syndrome * wilms tumour * williams * langer giedion * miller dieker * di-george * INVERSION * single chromosome breaks at two points * broken segment rearranges itself * inverting its position * pericentric * paracentric * RING CHROMOSOMES * ISOCHROMOSOMES * TRANSLOCATION * reciprocal translocation * exchange between two non-homologous chromosomes * after breakage and exchange of fragments * examples * translocation of chromosome 11 and 22 * robertsonian translocation * due to break near centromere in two acrocentric chromosomes * short arm of both chromosomes lost * but long arms get fused to form a new chromosome * chromosome number is reduced to 45 * examples * chromosome 13 and 14 * MOSAICISM / CHIMAERISM en/chromosome_disorders.txt Last modified: 2024/07/31 08:26by 127.0.0.1