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- | ====== MICROBIOLOGY | ||
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- | <columns 100% 25%> | ||
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- | * Bodyland Invasion | ||
- | * Bodyland routes of invasion ([[: | ||
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- | | bacteria cell wall | {{: | ||
- | | bacteria | ||
- | | bacterial toxin | {{: | ||
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- | * [[: | ||
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- | bacteria and cell interaction story or story of war between two cells (two persons analogy) | ||
- | bacteria is a unicellular organism hence it can be compared to a cell i.e., cell to person analogy | ||
- | bacteria is a bad person and human cells are good persons.there is a war between bacteria and human body immune cells. | ||
- | bacteria as compared to bad persons.as bad persons maintain bad gangs like gangsters. they also maintain groups and form colonies. | ||
- | as persons need nutrients and oxygen to survive bacteria also need oxygen to survive but there are some bacteria which does not need oxygen to survive and they are called anoerobic bacteria, persons or bacteria which live/work in the gastrointestinal tract or food passages(food industry) are called enterobacteria. | ||
- | As bad persons carry bombs and guns in their pockets,in a similar way they carry toxins and secrete inside the body which cause disease.the toxins are of two types | ||
- | exotoxin(exo(outside)+toxin) and endotoxin(endo(inside)+toxin).the toxins are named on the basis of their chemical nature or which part of the body they and on which type of cell they act. like leucocidal toxin -- (leuco-leucocytes + cidal-killing) toxin, enterotoxin-- entero(git) + toxin, | ||
- | cyto(cell) + toxin --- cytotoxin, | ||
- | hemo(blood)+lysin(lysis-break) --- hemolysin, | ||
- | epidermolytic toxin -- epidermo(epidermis-skin) + lytic(break) toxin. | ||
- | their groups are in the form of chains,form of circle, | ||
- | now let us talk about our enemy strategy and our defensive system. | ||
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- | our defence strategy system has three lines of defence 1. natural skin barrier, | ||
- | second line of defence is phagocytosis, | ||
- | third line of defence is lymphocytes and antibodies | ||
- | third line of defence comprises of police and soilders who are protecting our human body. they have specific badges called markers also called immune cell markers. | ||
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- | bad persons always carry guns and bombs with them these are equivalent to the toxins released by the bacteria. | ||
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- | A medieval castle would be a good analogy of the innate immune system. The high castle walls and the moat around the castle are designed to keep almost everything out. They act like the body's skin, mucous, and stomach acid. In the moat, we have alligators, which like the macrophages in the body, will basically eat anything. | ||
- | In our castle analogy, the adaptive immune system would include archers, spear-throwers, | ||
- | Working together: The innate system is the first line of defense. If the invader is stopped by the innate system, no disease will occur. If, however, the invader cannot be stopped by the innate system, the adaptive system is activated. If the adaptive system is successful, the body will recover. The adaptive system will also retain memory of the invader. So, if a second exposure to the invader occurs, the adaptive system will mount a greater and faster response, usually preventing disease. If neither the innate or adaptive systems are effective, death can occur. | ||
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- | * clostridium -- (kloster=spindle) | ||
- | * bacillus-- (rod shaped=bacilli) | ||
- | * hemophilus influenzae -- (hemo(blood)+philus(loving)) | ||
- | * diplo(pair)+ cocci(round) -- diplococcus | ||
- | * vibrio -- curved rods(vibrio-vibrate) | ||
- | * strepto(twisted or coiled) + coccus(round)--streptococcus molli(soft)+cutis(skin)= mollicutes | ||
- | * staphylococcus - staphy(bunch of grapes) + coccus(round) | ||
- | * corynebacterium diptheria -- coryne(club) + diphteria(leather) | ||
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